Before COVID-19, Big Pharma's reputation was suffering due to public outrage over mounting drug prices. Vaccine and anti-viral research went largely neglected by pharma companies because large-scale, one-shot vaccines for epidemics that generally affect poorer countries weren't profitable. When the COVID-19 pandemic abruptly arrived and became a wealthy country problem, federal funding started pouring in. Presently, polls show that Pharma's reputation has hit a new high.
We've been warned by experts repeatedly that a major pandemic is around the corner. Yet, many argue that Big Pharma and the National Institute of Health (NIH) was unprepared for the current pandemic, having shown "little interest in developing vaccines—or even antibiotic and antiviral medications—until the latest outbreak offered an opportunity to rake in public funding and turn out massive profits with minimal risk." After all, the NIH is the largest public funder of biomedical research in the world, investing more than $32 billion a year in research that "has led to breakthroughs and new treatments, helping people live longer, healthier lives, and building the research foundation that drives discovery."
Without a doubt, the pandemic has led many to question whether profits rather than needs drive the focus of the NIH and Big Pharma's medical research. With the government's heavy subsidizing for drug development and turning a blind eye to price gouging, pharmaceutical companies, their CEOs, and investors "stand to make billions from COVID vaccines, in one of the most spectacular examples yet of COVID profiteering." Indeed, scientists indicate that for years to come, we will need COVID-19 vaccines. It is unclear how much profit Big Pharma will make from COVID-19 vaccines, but Corporate Watch lays out five strategies pharmaceutical world leaders follow to make money. In the video below, from 2012, Goldacre illustrates five specific drugs where published data fails to reveal the entire picture of efficacy and side effects. As he points out in his book: "When trials throw up results that companies don't like, they are perfectly entitled to hide them from doctors and patients, so we only ever see a distorted picture of any drug's true effects." Emphasizing that "we like to imagine medicine is based on evidence, and the results of fair tests," Goldacre writes: "In reality, those tests are often profoundly flawed. We like to imagine that doctors are familiar with the research literature when in reality, much of it is hidden from them by drug companies. We like to imagine that doctors are well-educated, when in reality, much of their education is funded by industry. We like to imagine that regulators only let effective drugs onto the market, when in reality, they approve hopeless drugs, with data on side effects casually withheld from doctors and patients. Medicine is broken. And I genuinely believe that if patients and the public ever fully understand what has been done to them—what doctors, academics and regulators have permitted—they will be angry. On this, only you can be the judge."
It is important to understand that many prescription drugs are deemed effective based on research studies funded by their own creators. The clinical trials for the experimental COVID-19 vaccines are no different. Bad Pharma author Ben Goldacre believes the ramifications of this practice are widespread and very harmful. Goldacre asserts it is not just about the much-discussed shortcomings of Big Pharma alone—regulators, journal editors, academics, doctors and patient organizations are all implicated in failing to build a transparent, reliable, unbiased and safe knowledge framework for treatment decision making that can be shared by doctors and patients alike.